Before it
happens.

We built CORAAL, a tool that turns AI, physics and clinical data into decisions you can trust.

Request a demo Explore products

CORAAL is not yet CE marked and is not available for clinical use.

Virtual testing. Real confidence. Scroll ↓

Why Virtest

CORAAL: Every heart is unique.
So is every plan we make.

Transforming patient-specific data into real insight.

Automated image analysis

Automatic heart reconstruction
AI powered clinical and morphological measurements

Heart simulation

Device deployment
Blood flow simulation

Data management

Follow-up
Interactive analytics and reporting

+300 Patients analysed with CORAAL

11 Hospitals working with us

Explore our Products

powered by

Universitat Pompeu Fabra
Grow Venture Partners
Enisa
Hospital Clínic de Barcelona
Hospital de la Santa Creu i Sant Pau
European Commission
Universitat Pompeu Fabra
Grow Venture Partners
Enisa
Hospital Clínic de Barcelona
Hospital de la Santa Creu i Sant Pau
European Commission

Universitat Pompeu Fabra
Grow Venture Partners
Enisa
Hospital Clínic de Barcelona
Hospital de la Santa Creu i Sant Pau
European Commission
Universitat Pompeu Fabra
Grow Venture Partners
Enisa
Hospital Clínic de Barcelona
Hospital de la Santa Creu i Sant Pau
European Commission

The CORAAL ecosystem

One virtual heart. Every scenario, tested first.

01

LAAO

Left Atrial Appendage
Occlusion planning

5 minDevice deployment

20 minReport ready

24 hFlow simulation

3D virtual twin
Automated AI device sizing
Flow & thrombus-risk CFD
Interactive analytics

Discover CORAAL-LAAO

CORAAL is not yet CE marked and is not available for clinical use.

02

TAVI

Demo available from January 2027

Transcatheter Aortic Valve
Implantation planning

Anticipate how the valve will expand in each aortic root, and where leaks or conduction issues could appear.

Calcium distribution mapping
Best device fit algorithm
Flow simulation and device deployment

Discover CORAAL-TAVI

CORAAL is not yet CE marked and is not available for clinical use.

How it works

From CT scan to confident
decision.

See a sample report

01

Upload the patient’s data
02

Simulate on the virtual twin
03

Decide with confidence

One patient,
Multiple plans,
No surprises.

Optimize your pre-op workflow today. Simulate multiple strategies with CORAAL before the procedure begins.

See your next case
before it happens.

Book a demo and we’ll walk you through a real planning workflow with CORAAL.

Request a demo info@virtest.eu

CORAAL is not yet CE marked and is not available for clinical use.

The CORAAL ecosystem

VirtestApplications

Virtest presents CORAAL, an ecosystem of web-based tools for patient-specific computational modelling of complex structural heart interventions.

Request CORAAL demo How it works

CORAAL is not yet CE marked and is not available for clinical use.

01

LAAO

Left Atrial Appendage Occlusion

02

TAVI

Transcatheter Aortic Valve Implantation

IN DEVELOPMENT

03

Coming soon

A new CORAAL application in development

How CORAAL works

From the patient’s images to a shared decision.

The same four-step workflow runs across every CORAAL application, from the first scan to the report you share with your team.

01
Reconstruct the anatomy
AI-powered 3D morphological reconstruction
Medical images are turned into patient-specific 3D digital models of the left atrium and the left atrial appendage.
02
Plan the implantation
Personalised device selection and placement
Receive recommendations on device size and positioning, review the options and virtually implant the device of your choice. The final decision remains yours.
03
Simulate blood flow
Post-implantation hemodynamic simulation
Simulate blood flow after device implantation to assess hemodynamic changes and investigate potential flow-related complications.
04
Share your results
Interactive reports for clinical cooperation
Generate and share interactive reports with colleagues to review the implantation, with insights about possible post-procedural complications.

The CORAAL ecosystem

The applications

One platform, one workflow. Each CORAAL application brings patient-specific simulation to a different structural heart intervention.

01

LAAO

Left Atrial Appendage Occlusion

Advancing LAAC with intelligent procedural guidance. From automated anatomical measurements to patient-specific flow simulations and interactive clinical reports.

Device sizing
Leak & compression maps
Blood-flow simulation

Detailed product view

02

TAVI

Transcatheter Aortic Valve Implantation

Decoding aortic anatomy for personalised valve selection. From calcification risk assessment to virtual deployment of balloon-expandable and self-expanding valves.

Calcification mapping
Virtual deployment
Paravalvular leak risk

Detailed product view

IN DEVELOPMENT

03

A new patient-specific simulation application is currently being built by our team. More details will be announced soon.

Build in progressComing soon

Stay informed

01 CORAAL application

LAAO

Left Atrial Appendage Occlusion

Advancing LAAC with intelligent procedural guidance.

LAAOLeft Atrial Appendage Occlusion

01

Virtual LAAO planning

Advancing LAAC with intelligent procedural guidance.

CORAAL creates patient-specific digital models of the left atrium to simulate occluder implantation and help anticipate potential pre- and post-procedural complications. From automated anatomical measurements to flow simulations and interactive clinical reports, CORAAL-LAAO supports physicians throughout the LAAC workflow.

5 minDevice deployment

20 minReport ready

24 hFlow simulation

Request CORAAL demo Not yet CE marked · not available for clinical use.

CORAAL · Virtual implantationLAAO

01 · CORAAL-LAAO

What CORAAL will show you

Three complementary views of the same virtual implantation, ready to review with your team before the procedure.

A
**Leak map**Residual peri-device gaps between the occluder and the appendage wall.

B
**Compression map**How the device and the surrounding tissue interact once deployed.

C
**Blood flow**Post-implantation hemodynamics, coloured by blood-flow velocity.

02 CORAAL application

TAVI

Transcatheter Aortic Valve Implantation

Decoding aortic anatomy for personalised valve selection.

CORAAL-TAVI demo available from January 2027

TAVITranscatheter Aortic Valve Implantation

02

TAVI planning

Decoding aortic anatomy for personalised valve selection.

From calcium and anatomy to the optimal valve and deployment height. Evaluate the aortic root calcification pattern, simulate balloon-expandable or self-expanding prosthesis deployment, and predict paravalvular leakage before the procedure.

Balloon-expandableSelf-expandingDeployment heightCoronary obstruction risk

CORAAL-TAVI demo available from January 2027

Request CORAAL demo Not yet CE marked · not available for clinical use.

CORAAL · Valve deploymentTAVI

Coronary cuspsLCC · RCC · NCC

PredictionParavalvular leak

02 · CORAAL-TAVI

What would you be able to do with CORAAL-TAVI:

CORAAL-TAVI demo available from January 2027

01

Calcification and anatomy mapping

Key aortic anatomy and calcification patterns are quantified to recommend the best type of valve for each patient.

02

Propose new strategies

Suggest new approaches and simulate the new setting to see how the frame deforms.

03

Check it once the heart beats

Visualise blood flow with your chosen valve to assess the risk of leaks and HALT.

Born in research since 2016

More than 300 patients simulated with hospitals across Europe, and the peer-reviewed work behind every result.

The best plans start with the physician’s vision. At Virtest, we empower clinicians with the tools they need to make it a reality.

Xavier Freixa, MD, PhD
Head of Interventional Cardiology · Hospital Clínic de Barcelona
“Optimal placement is what makes the difference in the haemodynamic pattern after LAA occluder implantation. A favourable pattern is probably even more important than powerful antithrombotic treatment in avoiding events such as DRT. A software that shows you where to get the most favourable haemodynamics is something we have strongly missed.”

Craig Delaughter, MD, PhD
Physician · Cardiac Electrophysiologist at HeartPlace PA
“After proctoring over 200 LAAO implanters and nearly 1,000 LAAO implants, I am convinced that a pre-planning tool like Virtest improves the quality of closure, reduces procedural complications and improves procedural efficiency. As more implanters move toward a single operator, ICE-only workflow, pre-procedure planning becomes even more important. Virtest’s ability to simulate different potential closure solutions makes it highly valuable, especially in the most complex LAAO anatomy. If I were a patient undergoing an LAAO implant, I would insist that my implanter utilize this tool to achieve the best possible solution for me.”

Dabit Arzamendi, MD, PhD
Director of Interventional Cardiology · Hospital de la Santa Creu i Sant Pau
“We operate on three-dimensional anatomy, but we still plan on two-dimensional slices and a lot of intuition. CORAAL lets me rehearse the case before the patient is on the table: change the device, change the position, and see how it fits, in seconds.”

CORAAL in numbers

+300 Patients analysed with CORAAL

11 Hospitals working with us

11 Live cases at national and international congresses

12 Research projects with industry and academia

Clinical evidence

Clinical research

EuroIntervention 2026

Impact of device implantation depth on blood flow dynamics after left atrial appendage closure

Cepas-Guillén P, Albors C, Mill J, et al.

Multicentre study in 285 patients across 10 hospitals. Patient-specific CFD simulations identified the haemodynamic mechanisms associated with device-related thrombosis, and a CFD-based risk score predicted DRT better than implantation depth alone (AUC 0.81 vs 0.71).

Read the paper 2026;22(8):e444–e454

JACC: Case Reports 2025

The Role of Anticoagulants After Left Atrial Appendage Occlusion

Segarra-Queralt M, Mollà M, Barrouhou M, Olivares AL, Albors C, et al.

A patient with recurrent device-related thrombosis after LAAO, studied by combining haemodynamics with mechanistic models of thrombus formation and the effect of apixaban, to explain how device position and anticoagulation shaped what happened after the procedure.

Read the paper 2025;30(40):105838

Peer-reviewed research

Scientific papers & publications

Computers in Biology and Medicine 2025

In silico estimation of thrombogenic risk after left atrial appendage excision: towards digital twins in atrial fibrillation

Albors C, Terreros NA, Saiz-Vivó M, Zappala P, Terpstra MM, Olivares AL, et al.

Read the paper 2025;194:110483

PLOS Computational Biology 2024

Impact of occluder device configurations in in-silico left atrial hemodynamics for the analysis of device-related thrombus

Albors C, Mill J, Olivares AL, Iriart X, Cochet H, Camara O.

Read the paper 2024;20(9):e1011546

Scientific Reports 2024

The role of the pulmonary veins on left atrial flow patterns and thrombus formation

Mill J, Harrison J, Saiz-Vivó M, Albors C, Morales X, Olivares AL, Iriart X, et al.

Read the paper 2024;14(1):5860

FIMH · Lecture Notes in Computer Science 2023

Impact of blood rheological strategies on the optimization of patient-specific LAAO configurations for thrombus assessment

Albors C, Olivares AL, Iriart X, Cochet H, Mill J, Camara O.

Read the paper 2023:485–494

Journal of Interventional Cardiology 2022

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

Pons MI, Mill J, Fernandez-Quilez Á, Olivares AL, Silva E, et al.

Read the paper 2022;2022:9125224

Mathematics 2021

Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

Mill J, Agudelo V, Olivares AL, Pons MI, Silva E, Nuñez-Garcia M, et al.

Read the paper 2021;9(18):2304

Canadian Journal of Cardiology 2020

Impact of flow dynamics on device-related thrombosis after left atrial appendage occlusion

Mill J, Olivares AL, Arzamendi D, Agudelo V, Regueiro A, Camara O, et al.

Read the paper 2020;36(6):968.e13–968.e14

Get started

See the evidence applied to your own cases

Schedule a demonstration with our clinical solutions specialist and go through a patient-specific simulation step by step.

Request a Demo

CORAAL is not yet CE marked and is not available for clinical use.

Born in research.
Built for the clinic.

Virtest is a spin-off of the Physense group at Universitat Pompeu Fabra, Barcelona, developing its technology hand in hand with clinical teams.

Meet the team Join us

Virtual testing. Real confidence. Scroll ↓

Our story

No two hearts are alike. Like fingerprints.

In 2016, Dr. Xavier Freixa and Dr. Dabit Arzamendi brought us a question they faced every day: “Why do some patients with atrial fibrillation develop thrombi, and others don’t?”

Most of those thrombi form in the same place: the left atrial appendage. Closing it can protect these patients, but no two appendages are the same, and neither is the right way to close them.

They didn’t have an answer. Neither did we. But we couldn’t stop thinking about it.

Andy and Oscar started searching at the PhySense research group at Universitat Pompeu Fabra. A couple of years later, Jordi joined as a PhD student and Ainhoa as a software engineer. The four of us would go on to found Virtest. Back then, we were just a small research team with a question that had become ours too.

Then came our first lesson. We proudly brought Dr. Freixa our first result. It had taken a week. He looked at it and told us to come back when we had something he could actually use. He was right, and it shaped how we work to this day: no tool matters if it doesn’t fit the moment a heart team makes its decision.

So we started listening more than explaining, something we still do today. We built what clinicians needed, kept what helped, and changed what didn’t. The feedback was encouraging, and more and more cardiologists began asking us the same thing: can I use this with my patients?

We couldn’t say yes. It was still a research tool. But we didn’t want something we had built with them to end up in a drawer.

That’s when Carlos and Mònica joined us, before Virtest even existed, simply because they believed in it. Together, we built a great team, and took the step.

Today, we have simulated hundreds of patients with hospitals across Europe. We started with the left atrial appendage, but our goal is every structural heart intervention. And we are on our way to something that once sounded crazy: being there for every heart team, before it happens.

The Virtest Team

Our mission & vision

Helping heart teams and companies understand each patient’s heart, and decide with more knowledge and confidence before they intervene.

Mission

To help heart teams anticipate not only the intervention, but what comes after it, with tools built alongside clinicians and designed to fit the way they make decisions.

Vision

Virtual testing as a natural step before every structural heart intervention, so every decision starts from the patient’s own heart.

The future

Taking what we started with the left atrial appendage to more structural heart procedures, and growing our tools as clinical practice evolves, always together with the heart teams who use them.

Our pillars

What guides us comes from where we started: engineers and clinicians working side by side, on real questions, for real patients.

Anticipation

Exploring what could happen, during the intervention and after it, so every team is better prepared.

01

Scientific rigour

Precise in what we do, honest in what we say. We never claim more than we can show.

02

Collaboration

Engineers and clinicians, side by side. Listening more than explaining, as we have since day one.

03

Human impact

Technology that supports medical judgement, never replaces it. Because behind every case there is a patient.

04

our people

The team

Engineers, scientists and regulatory experts who learned early to listen to clinicians, and still do. Together with the cardiologists who have been with us since day one.

Jordi Mill Co-founder & CEO

Carlos Albors CTO

Mònica Font COO · Quality & Regulatory

Ainhoa M. Aguado Co-founder & Head of Software

Andy L. Olivares Co-founder & Simulation Lead

Nerea Ferrara Software Engineer

Oscar Camara Co-founder & Scientific Advisor

Careers at Virtest

Want to be part
of it?

We are always interested in people working in biomechanical engineering, medical image processing, computational fluid dynamics and software development who want to change how cardiovascular medicine is planned.

See open positions Send an open application

Experience Virtest cardiac simulation.

See a real planning workflow with CORAAL, from CT scan to confident decision.

Request a demo

CORAAL is not yet CE marked and is not available for clinical use.

Get In Touch

Let's work together.

Get in touch if you would like to work with us, explore a clinical collaboration, discuss our technology, or request a demonstration.

First Name

Surname

Organization / Hospital

Role

Professional Email

Country

Reason for Contact

Message

We will use the details you send us only to answer your enquiry. Write to info@virtest.eu to have them deleted.

EMAIL: info@virtest.eu

HEADQUARTERS: Carrer Roc Boronat, num 138, oficina 51.010, 08018 Barcelona — (Barcelona), Spain

ENTITY: Virtest Technologies S.L.

Interactive Demonstration

See patient-specific cardiac simulation in action.

Experience how Virtest's CORAAL-LAAO platform transforms DICOM image files into virtual left atrial replicas, detailed flow vectors, and real insight reports.

What to Expect During the Demo

1
Product Overview Key features of CORAAL-LAAO & CORAAL-TAVI platforms.
2
Virtual Twin Setup Raw DICOM upload to automatic 3D replica.
3
Physical Simulation 10-minute device deployment & 24-hour CFD flow vectors.
4
Interactive Report 20-minute real insight report generation.

Full Name

Professional Email

Institution / Company

Primary Application Interest

We will use the details you send us only to answer your enquiry. Write to info@virtest.eu to have them deleted.

CORAAL is not yet CE marked and is not available for clinical use.

FAQ

Questions we often hear

Still have questions?

Talk to us, or see CORAAL in action.

Request a demo Talk to us

CORAAL is not yet CE marked and is not available for clinical use.

Media Hub

Period

Press release

Grow Venture Partners joins Virtest Technologies S.L. as strategic investor

Strategic backing accelerates clinical rollout and regulatory pathways for CORAAL-LAAO across European cardiac centres.

2025-10-15

In the news

The IDEAL multi-centre retrospective study reaches 300+ patients

More than 300 retrospective cases across 11 partner hospitals are being analysed to validate CORAAL-LAAO flow and positioning predictions.

2026-01-28

In the news

CORAAL-LAAO guided live procedure transmitted from Hospital Universitario de Salamanca

Operators walked through the pre-procedural simulation and the positioning it supported during a complex appendage case.

2025-12-05

Congresses & workshops

Where to find us

London, United Kingdom Upcoming

PCR London Valves 2026

November 22 – 24, 2026

Participation confirmed. Come and meet the team.

Frankfurt, Germany Past

CSI Frankfurt 2026

June 24 – 27, 2026

Virtest symposium: “Go with the Flow: in-silico hemodynamic planning for high-risk structural interventions.”

Barcelona, Spain Past

RIICE Focus 2025

November 14 – 15, 2025

Live case transmission and workshop on CORAAL-TAVI calcification and expansion mechanics.

Madrid, Spain Past

CSC Estructural 2025

September 18 – 19, 2025

Hands-on demonstration room for interventional fellows working with digital twin occluder placement.

Blog

Notes from the lab
and the cath lab.

Short reads on patient-specific simulation: how a case is planned, what the numbers mean and what we are learning with the clinical teams we work with.

Coming soon

Reading a compression map without guessing

What under, normal and over compression look like on the same anatomy, and why the decision is easier before the procedure.

Draft

Coming soon

From CT study to virtual twin in minutes

How automatic segmentation turns a routine cardiac CT into a model the whole team can work with.

Draft

Coming soon

What blood flow tells us after the implant

Stasis zones, wall shear stress and why the flow left behind matters as much as the fit.

Draft

The first articles are on their way.

Write to us and we will let you know when they are published, or tell us what you would like to read about.

Get in touch

Build the future of patient-specific cardiac care.

VIRTEST brings together biomechanical engineering, computer science, software development and medicine to help doctors understand each heart better before they intervene. We are looking for people who combine scientific rigor with a practical mindset, who enjoy solving complex problems and want to see their work used in real clinical decisions. If that sounds like you, we’d love to hear from you.

Open positions

We are always interested in hearing from engineers, computational scientists and clinical specialists. Tell us what you do and where you would like to take it.

Send us your profile

Work culture

Scientific rigor, built for the clinical day-to-day.

We are a team of engineers, computational scientists and clinical experts, born from academic research at Universitat Pompeu Fabra.

Rigorous, and on clinical time

We hold ourselves to scientific precision, but a highly accurate model that arrives too late is of no use: clinical decisions are made on clinical time. Everything we build has to be rigorous, fast enough and practical enough to fit into real clinical workflows.

Side by side with clinicians

The clinical decision is our driver. We work next to the people who take it, so that our technology supports medical judgement and never replaces it.

Clear about what it can and cannot do

We say clearly what our technology can do, and what it cannot. We are proud of the science behind it, and even more motivated by its impact on patients.

Before ithappens.

CORAAL: Every heart is unique. So is every plan we make.

Automated image analysis

Heart simulation

Data management

One virtual heart. Every scenario, tested first.

Left Atrial AppendageOcclusion planning

Transcatheter Aortic ValveImplantation planning

From CT scan to confident decision.

Upload the patient’s data

Simulate on the virtual twin

Decide with confidence

One patient,Multiple plans,No surprises.

See your next casebefore it happens.

From the patient’s images to a shared decision.

Reconstruct the anatomy

Plan the implantation

Simulate blood flow

Share your results

The applications

Left Atrial Appendage Occlusion

Transcatheter Aortic Valve Implantation

Loading…

Left Atrial Appendage Occlusion

Virtual LAAO planning

What CORAAL will show you

Transcatheter Aortic Valve Implantation

TAVI planning

What would you be able to do with CORAAL-TAVI:

Calcification and anatomy mapping

Propose new strategies

Check it once the heart beats

Born in research since 2016

The best plans start with the physician’s vision. At Virtest, we empower clinicians with the tools they need to make it a reality.

Xavier Freixa, MD, PhD

Craig Delaughter, MD, PhD

Dabit Arzamendi, MD, PhD

CORAAL in numbers

Clinical research

Impact of device implantation depth on blood flow dynamics after left atrial appendage closure

The Role of Anticoagulants After Left Atrial Appendage Occlusion

Scientific papers & publications

In silico estimation of thrombogenic risk after left atrial appendage excision: towards digital twins in atrial fibrillation

Impact of occluder device configurations in in-silico left atrial hemodynamics for the analysis of device-related thrombus

The role of the pulmonary veins on left atrial flow patterns and thrombus formation

Impact of blood rheological strategies on the optimization of patient-specific LAAO configurations for thrombus assessment

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

Impact of flow dynamics on device-related thrombosis after left atrial appendage occlusion

See the evidence applied to your own cases

Born in research.Built for the clinic.

Our story

Our mission & vision

Mission

Vision

The future

Our pillars

Anticipation

Scientific rigour

Collaboration

Human impact

The team

Want to be partof it?

Experience Virtest cardiac simulation.

Let's work together.

See patient-specific cardiac simulation in action.

What to Expect During the Demo

Questions we often hear

Still have questions?

Media Hub

Grow Venture Partners joins Virtest Technologies S.L. as strategic investor

The IDEAL multi-centre retrospective study reaches 300+ patients

CORAAL-LAAO guided live procedure transmitted from Hospital Universitario de Salamanca

Where to find us

PCR London Valves 2026

CSI Frankfurt 2026

RIICE Focus 2025

CSC Estructural 2025

Notes from the laband the cath lab.

Reading a compression map without guessing

Before it
happens.

CORAAL: Every heart is unique.
So is every plan we make.

Left Atrial Appendage
Occlusion planning

Transcatheter Aortic Valve
Implantation planning

From CT scan to confident
decision.

One patient,
Multiple plans,
No surprises.

See your next case
before it happens.

Born in research.
Built for the clinic.

Want to be part
of it?

Notes from the lab
and the cath lab.